PGx
Pharmacogenomics Testing
Pharmacogenomics is the study of genetic variations that influence an individual’s response to medications. Each person responds uniquely to treatment so the same approach may not be effective or may cause adverse side effects in other patients. Understanding this information is helpful to physicians in developing a strategy to optimize drug therapies. Data concerning a patient’s genotype are used to maximize drug efficacy while minimizing adverse drug effects and drug-drug interactions.
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What is pharmacogenomics (PGx)?
In short, pharmacogenomic (PGx) testing saves lives, by helping physicians prescribe the right medication for a patient by taking the trial & error out of prescribing and thus decreasing the time it would take to receive proper treatment.
Many patients have experienced the feeling that they cannot tolerate a medication or may feel that it is not helping them. This can cause a patient to have to return to their doctor over and over to try to find a medication that works better for them or has fewer side effects. The PGx test will scientifically determine how your body will metabolize different medications. The doctor can then prescribe a more effective and safer medication from the first appointment.
PGx Test can be useful for understanding the impact of the medications that are being used today but can also help for future treatments. This is because many commonly prescribed medicines are impacted by a handful of genes so there will be overlap for results and it is highly likely that the result of one PGx test will be useful for future treatments. Thus, the PGx test results are not only important for the medication which prompted the testing but potentially for other medicines prescribed in the future. Because a PGx test result can help inform other treatment decisions in the future for a patient’s care, results should be shared with other providers and potentially even the patient’s pharmacist.
Who benefits from PGx testing?
- Patients that experience less than optimal results from prescribed medications.
- Patients with a personal or family history of adverse drug reactions in response to certain medications.
- Patients taking multiple prescription medications for multiple chronic conditions.
Adverse drug reactions are a leading cause of death nationwide. The FDA highlights pharmacogenomics data for more than 130 prescription medications indicating their strong support for testing. Pharmacogenomic (PGx) Testing provides evidence-based, actionable data for clinicians. This will help predict if a patient is likely to experience an adverse medicine reaction or not respond to a given medicine at all.
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What can you expect for results from PGx testing?
Why do drugs work for some people while not for others? Everyone’s metabolism is different.
- Extensive (normal) Metabolizer
- Intermediate Metabolizer
- Poor Metabolizer
- Ultra-rapid Metabolizer
Based on genetics, everyone has the potential to respond to medication differently:
- Medication is ineffective
- Patient experiences unexpected reaction
- Serious side effect occurs
- A higher dosage is needed
- A lower dosage is needed
Why play trial and error with your
medication when you can know for sure?
Talk With Tesis Biosciences
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