Do you feel overwhelmed when trying to diagnose primary immunodeficiencies (PIDs)? Have you been looking for a faster, more cost-effective way to get test results? Today’s advances in technology provide physicians with an alternative option: targeted next-generation sequencing.
Targeted Next Generation Sequencing (NGS) is a cutting-edge technique that offers both convenience and quality diagnostics, enabling you to make faster decisions which are crucial in ordering the correct treatments for your patients. Here are 7 reasons physicians should consider using this revolutionary genetic testing method for PID Immunodeficiency.
By sequencing the specific genes using Tesis Biosciences customizable panels we can provide a much more detailed picture of your patient’s immunologic status. This allows healthcare providers to make more informed decisions regarding diagnosis and treatment.
Targeted NGS can provide quality comprehensive information regarding the patient’s family history and potential risks of passing on genetic diseases. By testing a range of genes associated with PID Immunodeficiency, physicians can better understand the patient’s family medical history. It also explains any potential risks that may be associated with passing on certain genetic diseases.
By sequencing multiple aspects of the immune system genome, a clinician can better understand how a patient’s body interacts with different pathogens and medications. This can allow for more tailored treatments, improving outcomes in primary immunodeficiency.
Targeted NGS has revolutionized genomic medicine due to its affordability. The cost per test is often less when compared to other popular standard tests, making it an attractive option for those seeking cutting-edge personalized genomics. With Targeted NGS, practitioners can access an accurate and comprehensive picture of genetic health, enabling them to better tailor treatment plans based on their patient’s genetic makeup.
Tesis Biosciences’ offers healthcare providers a way to access clinical-grade genomics that offers insights into disease prevention, diagnosis and treatment. Targeted NGS is quickly becoming the testing technology of choice in precision medicine.
Here are reasons targeted NGS is an essential tool in guiding clinical decision-making for patients with primary immunodeficiency (PID) disorders:
- This technique uses sequencing technologies, to identify rare genetic variants underlying these conditions.
- Immunodeficiency panel is simple non-invasive test.
- Tests can be performed on patients in the comfort of their healthcare provider’s medical office.
- Targeted NGS can detect diverse genetic defects, resulting in quicker and more precise diagnoses than other methods.
- Detection of a relevant mutation allows for definitive diagnosis, thoughtful management of treatment and long-term outcomes planning to improve prognosis and quality of life.
- It can be used to confirm suspicions of a patient’s phenotype before the confirmation of the genotype.
- NGS is an invaluable tool that physicians should use when considering the care of their PID patients.
Targeted NGS is becoming a solution to diagnosing rare forms of immunodeficiency because of the following reasons:
- NGS can be used to identify mutations and discover novel gene variants in genes that are associated with rare forms of immunodeficiency.
- Targeted NGS can be used to detect copy number variations (CNVs) that could indicate the presence of a rare form of immunodeficiency
- It can be used to detect changes in gene expression levels.
- Targeted NGS can be used to assess the functional impact of gene variants on protein function, which could be important in the diagnosis of rarer forms of immunodeficiency
- It can be used to identify aberrant pathways or networks that could be contributing to the immunodeficiency phenotype in the patient
NGS Can Be Used to Monitor Disease Progression and Response to Therapy in PID Patients
It is a powerful tool to monitor disease progression and evaluate the response to therapy in primary immunodeficiency disorder (PID) patients. Utilizing NGS, physicians can look at specific intervals of DNA, called regions of interest, that may be impacted by genetic mutations connected to PIDs. This type of sequencing allows for a more detailed genetic analysis.
With NGS, healthcare providers have greater insight into identifying diseases, matching therapies, clinical research trials to speciﬁc patient needs, and assessing health outcomes so that treatments can be fine-tuned according to individualized patient characteristics.
Furthermore, by utilizing this strategy in research settings, knowledge about the disease process in individuals and cohorts can be gained — providing opportunities for earlier interventions and better health outcomes on a larger scale.
Targeted NGS is a powerful screening tool that can provide more information to physicians about their patients with PID Immunodeficiency. Next-generation sequencing panel can help improve patient outcomes by providing actionable insights that guide clinical decision-making. If you are a physician treating patients with PID immunodeficiency, we encourage you to consider targeted NGS as a part of your diagnostic workup. Our team at Tesis Biosciences Services in Colorado Location would be happy to answer any questions you have and provide additional resources. Contact us today for more information.